Graduation thesis

・Koichi KIMURA
「Development of an atmospheric pressure infrared laser electrospray ionization for mass spectrometry of membrane proteins」
・Sota KONDO
「Development of athermal and highly efficient removal technique of caries using Q-switched Er:YAG laser」
・Takuma NOGUCHI
「Thermal damage to evaluate the safety of colorectal endoscopic submucosal dissection using carbon dioxide laser」
・Tugs OYUNBILEG
「In silico evaluation of nanosecond-pulsed laser skin treatment」

 Master's thesis

・Yasunari IGUCHI
「Development of a Continuous Flow Infrared Laser Desorption/Ionization Method for Rapid Liquid Chromatography/Mass Spectrometry of Biomolecules」
・Kota SHIMIZU
「Development of Less-Invasive Treatment of Dental Caries Using a Nanosecond-Pulsed Laser at the 3 μm Wavelength Band」
・Homare HASHIYA
「Development of atmospheric pressure infrared laser ionization for analysis of membrane proteins using online liquid chromatography/mass spectrometry」
・Keisuke HARA
「Determination of Photochemical Properties of Photosensitizers for Development of Treatment Planning Simulation of Photodynamic Therapy」
・Mina FUKUDOME
「Investigation on Mechanism of Sonodynamic Therapy for Deep Cancer」
・Tasuku FURUYAMA
「Investigation of the Mechanism in Photodynamic Therapy with Replication-Deficient Sendai Virus Particles and Protoporphyrin IX Lipid」
・Daichi MATSUI
「Development of a Multispectral Angioscopic System at Wavelengths around 1200 nm for Objective Diagnosis of Atherosclerotic Plaque」

 Graduation thesis

・Misako IWAMOTO
「Spectroscopic measurement of scattering angular distributions for anisotropy factors in biological tissues」
・Sachiko SAITO
「Encapsulation of a photosensitizer into inactivated Sendai virus particles for photodynamic therapy of prostate cancer」
・Sakiko SHIRATSUKI
「Comparison study of thermal damages on porcine rectum caused by incision using CO2 laser and electrosurgical knife in endoscopic submucosal dissection for colon cancer」
・Shusei NOMURA
「Laser Ionization Mass Spectrometry Using Zeolite Matrix for Simultaneous Imaging of Multiple Anticancer Drugs」
・Youngsoon HONG
「Induction of photosensitizer into inactivated viral vector for fast drug delivery」
・Kenji MATSUDA
「Infrared spectroscopic evalustion of matrix cystal polymorph to enhance the sensitivity of drug imaging with mass spectrometry」

 Master's thesis

・Mizuho INAI
「Rationally designed combination therapy for prostate cancer: replication-deficient viral particle allow efficient delivery of photosensitizer while ensuring direct virus cytotoxicity」
・Eishi IMOTO
「Development of Imaging Mass Spectrometry Using Laser Desorption/Ionization for Pharmacokinetics of Transdermal Vaccination」
・Ayaka IWADE
「Comparison of Atmospheric Pressure Laser Ionization of Biomolecules Using 3 and 6 ?m-band lasers for High-Speed Mass Spectrometric Analysis」
・Ayane OKAZAKI
「Simulation of Ion Trajectories for Improvement of Aberrations in Stigmatic Imaging Mass Spectrometer」
・Daichi FUKUTOMI
「Determination of Highly Accurate Optical Properties of Biological Tissues for Quantitative Simulation of Light Propagation」
・Naoki MORIGUCHI
「Enhancement of Ionization EfficiencyUsing Zeolite for Drug Imagingwith Laser Desorption/Ionization Mass Spectrometry」
・Masato YOSHIMORI
「Evaluation of Intravascular Temperature DistributionUsing Computational Simulationfor Laser Treatment of Varicose Veins」

 Doctor's thesis

・Keisuke HASHIMURA
「Tissue optics in the mid-infrared region for selective removal of atherosclerotic plaque toward novel laser angioplasty」

 Graduation thesis

・Yasunari IGUCHI
「Development of an atmospheric pressure infrared laser ionization method for rapid analysis of biomolecules by liquid chromatography-mass spectrometry」
・Keisuke HARA
「Optimization of photodynamic therapy based on a singlet oxygen concentration simulation」
・Daichi MATSUI
「Development of near-infrared multispectral angioscope for the detection of atherosclerotic plaques」

 Master's thesis

・Yoichiro KARIYAMA
「Development of Photodynamic Therapy Simulation Model Considering Photobleaching Constant of a Photosensitizer」
・Hiroki KANNEN
「Development of Laser Ionization Imaging Mass Spectrometry for Drugs Administered in Cancer Cells」
・Daisuke KUSAKARI
「Development of a laser Delivery System for Establishment of Safe and Stable Gastrointestinal Endoscopic Laser Therapy」
・Junya TAKADA
「Development of Optimal Laser Vaporization of the Prostate Based on Tissue Optics」
・Ryo NAGAO
「Development of near-inflared Multispectral Imaging System for Diagnosis of Atherosclerotic Plaque」
・Hitomi YABE
「Development of an evaluation model of photodynamic therapy for cancer based on energy density and concentration of reactive oxygen species」
・Masaya YAMAUCHI
「Development of a novel photosensitizer having an antitumor effect and its application to photodynamic therapy for anticancer drug resistant prostate cancer cells」

 Graduation thesis

・Eishi IMOTO
Development of Imaging Mass Spectrometry Using Laser Desorption/Ionization for Pharmacokinetics of Transcutaneous Medicine」
・ Ayaka IWADE
「Investigation of Mid-Infrared Wavelength Range Used for Atmospheric Pressure Laser Ionization for Mass Spectrometry of Peptide Aqueous Solution」
・ Kota SHIMIZU
「Evaluating the ablation property of bovine dentin using Q-switched Er:YAG laser at wavelength of 2.94 μm」
・ Daichi FUKUTOMI
「Calculation of high-precise scattering spectra by an integrating sphere setup considered angular distribution of diffuse reflection light」

 Master's thesis

・ Rinna KAWAGUCHI
「Investigation of detection method of blood vessels to improve the safety of endoscopic submucosal dissection using carbon dioxide laser」
・ Tetsuya KITA
「Less-invasive treatment of dental caries using nanosecond pulsed laser at wavelength of 5.85 μm」
・ Ryuji HIRAGUCHI
「Development of an Atmospheric Pressure Laser Ionization Method Using a Mid-Infrared Tunable Laser for Rapid Analysis of Biological Polymers」
・ Takuro HORIBE
「Investigation of improvement methods in the estimation error of scattering coefficient in determination of optical properties of biological tissues」

 Graduation thesis

・ Yoichiro KARIYAMA
「Optical properties measurement of tumor tissues grown on the chorioallantoic membrane of chicken eggs for alternative to tumor-bearing mouse」
・ Hiroki KANNEN
「Development of Imaging Mass Spectrometry using Laser Desorption/Ionization for Evaluation of the Effect of the Cancer Drug」
・ Daisuke KUSAKARI
「Development of a power sensor integrated with an optical fiber for stabilizing output power in endoscopic therapy using carbon dioxide laser」
・ Junya TAKADA
「Quantitative evaluation of safety and effectiveness of laser treatment for benign prostatic hyperplasia using a high-power laser diode at the wavelength of 980 nm」
・ Ryo NAGAO
「Investigation of optimal wavelengths for diagnosis of atherosclerotic plaque with near-infrared spectroscopic Imaging」
・ Masaya YAMAUCHI
「Fundamental investigation of photodynamic therapy for prostate cancer using a new photosensitizer」

 Master's thesis

・Kota OMIYA
「Real-time imaging and quantitative evaluation using optical property of laser coagulated area of biological tissue by optical coherence tomography」
・Akiko KITAYABU
「Development of diagnostic technique for arteriosclerosis with near-infrared hyperspectral imaging」
・Saki NOZOE
「Ex vivo investigation of optimal irradiation parameters in endovenous laser ablation」
・ Keisuke HASHIMURA
「Development of less-invasive laser angioplasty with a quantum cascade laser in the 5.7 μm wavelength range」
・ Masaya YOSHIOKA
「Development of monitoring method for measurement of acetate and concentration of microorganisms in activated sludge by near infrared spectroscopy」

 Doctoral thesis

・ Makoto SAKAI
「Less-invasive Cancer Therapy by the Combination of Drug Delivery System and Quantum Energy
・ Norihiro HONDA
「Development of the measurement system of biological tissue optical properties for medical laser applications」

 Graduation thesis

・Rinna KAWAGUCHI
「Investigation of optical detection method ofvessels in endoscopic submucosal dissection using carbon dioxide lasere」
・Tetsuya KITA
「Optimum irradiation condition for less-invasive treatmentof carious dentin using nanosecond pulsed laser with 5.8μm wavelength range」
・ Keisuke HASHIMURA
「Less-invasive quantum cascade laser angioplasy with the wavelength range of 5.7 μm」
・ Tomonori HAMANAKA
「Investigation of Sarnple Preparation and Image Processing for Imaging Mass Spectrometry Using Laser Desorptionllonization」
・ Ryuji HlRAGUCHI
「Development of Atmospheric Pressure Laser Ionization using Mid-infrared Tunable Laser for Biomolecular Mass Spectrometry」
・ Takuro HORIBE
「Evaluating the optical properties of coagulated turnor tissue after surgical removal in the visible to near-infrared wavelength range」
・ Naoki MORIGUCHI
「Investigation of Ionization Assisting Reagents for Application ofImaging Mass Spectrometry Using Laser Desorptionllonization to Pharmacokinetics」

 Master's thesis

・ Atsushi INOUE
「Development of the optical phantom of a human lumbar disc tissue for the laser treatment of disc herniation」
・ Masayuki SAIKI
「Minimal invasive treatment of carious dentin using a mid-infrared tunable pulsed laser」
・ Takuya NANJO
「Investigation of improvement methods in the estimation error of scattering coefficient in determination of optical properties of biological tissues」
・ Satoshi FURUKAWAE
「Investigation of the Influence of Solvents for Ionization of Peptides in Matrix-Assisted Laser Desorption/Ionization」
・Keiichiro YAMADA
「Safety assessment of submucosal dissection using carbon dioxide laser and expanding the indication to esophagus and large intestine」

 Graduation thesis

・ Junya ISHIDA
「Fundamental investigation for analysis of pharmacokinetics using Stigmatic Imaging Mass Spectrometry」
・ Kota OMIYA
「Real-time imaging of laser coagulated area of biological tissue by optical coherence tomography」
・ Akiko KITAYABU
「Development of arteriosclerosis diagnosis system using near-infrared hyperspectral imaging」
・Masatoshi TAKATA
「Selective Removal of Carious Dentin by using the High Power Quantum Cascade Laser with 5.7 m Wavelength Range」
・Saki NOZOE
「Quantitative analysis of Endovenous Laser Treatment based on Human Vein Optical Properties」

 Master's thesis

・ Yohei KOBAYASHI
「Development of Integrating Sphere Optical System for Tissue Optical properties contributing to High Performance Phototherapy」
・ Naohiro FUJIMOTO
「Less Invasive Cancer Therapy with Quantum Beam and Non-viral Vector」
・ Hidetoshi YOSHIMURA
「Development of Imaging Mass Spectrometry Using Laser Desorption/Ionization for Observation of the Distributions of Molecules in Biological Tissue」
・ Satoshi WATANABE
「Development of a medical carbon dioxide laser system to expand the indication of endoscopic submucosal dissection」

 Graduation thesis

・ Atsushi Inoue
「Primary investigation of the safe percutaneous laser disc decompression using the laser diode with a wavelength at 405 nm」
・ Masaiki Saiki
「Selective treatment technique of carious dentin using a nano second pulsed laser with 6 μm wavelength range」
・ Takuya Nanjo
「Measurement of the optical properties of biological soft tissues and application for laser coagulation therapy」
・ Yusaku Fujii
「Development of ionization method for biopolymers with infrared and ultraviolet lasers」
・ Keiichiro Yamada
「Endoscopic submucosal dissection using CO₂ laser and submucosal injection solution for esophagus cancer」

 Master's thesis

・ Taisuke Ikawa
「Hyperspectral imaging of subcutaneous fat tissue using a near-infrared super continuum light source」
・ Hideki Tsukimoto
「Development of less-invasive laser angioplasty using nanosecond pulsed laser at 5.75 μm」
・ Norihiro Honda
「Development of the tissue optical property measurement system in visible and NIR wavelength region」
・ Keisuke Matsumoto
「Development of a diagnostic system based on spectroscopy using a high-intensity mid-infrared tubable laser」

 Doctoral thesis

・ Hirofumi Nagao
「Development of a tandem mass spectrometer for probing high-energy electron transfer dissociation」

 Graduation thesis

・ Yohei Kobayashi
「Quantitative determination of trans fatty acids using infrared spectroscopy assisted by gas chromatograph」
・ Satoshi Fukumoto
「Development of polymer film for infrared laser induced ionization/desorption」
・ Naohiro Fujimoto
「Primary investigation of low-dose efficient boron neutron capture therapy」
・ Hidetoshi Yoshimura
「Development of a position and time sensitive ion detector for stigmatic imaging mass spectrometry」
・ Satoshi Watanabe
「Fundamatal study about selective submucosal dissection using carbon dioxide laser」

 Master's thesis

・ Akinori Kimura
「Measurement of optical properties of laser treated biological tissues by Inverse Adding Doubling method」
・ Makoto Sakai
「Basic in vitro investigation of novel cancer therapy with quantum beam」
・ Ren Suzuki
「Imaging mass spectrometry using a homogenizing system for the laser intensity distribution and direct laser desorption/ionization techniques」
・ Yutaka Tomioka
「Photodynamic effect on immunocompetent cells」
・ Haruyuki Himeno
「Regulation of the insulin secretion by visible laser irradiation to pancreatic β-cell line」
・ Tamami Fujita
「Development of a novel time-of-flight mass spectrometry by infrared laser desorption/ionization」
・ Shinya Yamada
「Development of the elemental techniques for novel diagnostic and therapeutic system of gallstones using a mid-infrared tubanle laser」

 Doctoral thesis

・ 金井 大造
「自由電子レーザーパルス制御による光-生体相互作用機序の解明に向けたシステム開発」

 Doctoral thesis

・ Katsunori Ishii
「Quantitative treatments of biological tissues by mid-infrared photon induced molecular vibrations」